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Thirty two newborn buffalo calves with an average live body weight of 40 kg were divided into four experimental groups: control group, without any treatment; selenium group, was injected with 5 mg selenium (Se)/head biweekly; vitamin E group, supplemented with 2000 IU of vitamin E weekly in milk and Se+E group, treated with both Se and vitamin E. All calves were fed whole milk, concentrate starter and berseem. Blood samples were collected from jugular vein of calves at 1, 3, 5, 9 and 13 weeks of age. The experiment continued until weaning calves at 105 days of age. The average daily gains were improved nonsignificantly by 6.4, 14.5 and 8.1% for Se, vitamin E and Se+E groups, respectively compared with control. Also, the respective treatments improved feed conversion by 17.99, 17.45 and 18.83%. Plasma Se concentrations of calves injected with Se or Se+E were significantly (P
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